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2019年

2018年

2017年

2014年

2013年

2012年

  • Understanding the lipid-digestion process in the GI tract before designing lipid-based drug-delivery systems
  • Lipid matrix by hot melt extrusion: a practical industrial solution for solid dispersion
  • Synergy effect of two glycerides to increase stability and ethanol resistance of sustained release matrix tablets
  • Compritol® 888 ATO lipid matrices for sustained release processed by hot melt extrusion
  • Development of a novel co-culture cell model able to mimic variable permeabilities of the human intestine and tolerate biorelevant media
  • Characterization of a new self-emulsifying excipient to expand formulation options for poorly soluble drugs: Gelucire® 48/16
  • Sustained-release of diclofenac sodium from wet granulated Compritol® 888 ATO matrix tablets
  • Development and evaluation of sustained release Compritol® 888 ATO matrix mini-tablets

2011年

2010年

  • Diluent effects on drug release from sustained release Compritol® 888 ATO tablets
  • Gastro-intestinal lipolysis of lipid-based excipients intended for oral drug delivery of poorly water soluble drugs
  • Specific assay of carboxyl ester hydrolase using PEG esters as substrate
  • An investigation into the mechnism of dissolution rate enhancement of poorly water soluble drugs from spray chilled Gelucire® 50/13 microspheres

2009年

  • Lauroyl polyoxylglycerides, functionalized coconut oil, enhancing the bioavailability of poorly soluble active substances
  • Vaginal cream formulation for the prevention of HIV infection for women in developing countries
  • In vitro gastrointestinal lipolysis of four formulations of piroxicam and cinnarizine with the self-emulsifying excipients Labrasol® and Gelucire® 44/14
  • Influence of drug polarity upon the solid-state structure and release properties of self-emulsifying drug delivery systems in relation with water affinity

2008年

  • Guidelines to formulate OTC drugs in topical emulsions with improved sensorial properties
  • Effect of Labrafil M2125CS and its digestion products on viability of Caco-2 cells
  • Influence of the particle size of aqueous dispersions of Labrasol® on the activity of digestive lipases
  • Lipolysis of the semi-solid self-emulsifying excipient Gelucire® 44/14 by digestive lipases
  • Approaches for the development of solid and semi-solid lipid-based formulationns

2007年

  • In vitro lipolysis of the self-emulsifying excipient, Labrasol®
  • Comparative study on digestive lipase activities on the self-emulsifying excipient Labrasol®, medium chain glycerides and PEG esters

2006年

  • Structural and thermal characterization of glyceryl behenate by X-ray diffraction coupled to differential calorimetry and infrared spectroscopy
  • Pharmaceutical surfactants in biorelevant media: impact on lipolysis and solubility of a poorly soluble compound, danazol
  • In vitro evaluation of pharmaceutical surfactants fate during lipolysis and its effects on solubilization of a poorly water soluble compound, danazol
  • Solubilization of a poorly soluble model drug during in vitro lipolysis of macrogol glyceride surfactants at fed and fasted state conditions
  • The fate of some surfactants during in vitro lipolysis and the effect on solubilization of a poorly soluble model compound
  • Interest of carriers for the development of solid self-emulsifying drug delivery systems

2005年

  • Influence of poloxamers on the dissolution performance and stability of controlled-release formulations containing Precirol® ATO 5
  • Interest of multifunctional lipid excipients: case of Gelucire® 44/14
  • Modification of the drug release of ibuprofen by hot melt coating with mixes of Compritol® 888 ATO and non ionic surfactant
  • Development of tablets with self-emulsifying drug delivery systems (SMEDDS)
  • Poloxamers influence the dissolution and stability of lipid matrices of Precirol® ATO 5
  • Contribution of contact angle measurements and microscopic studies to the knowledge of self-emulsifying drug delivery systems
  • Bibliography on Gattefossé’s products. 2004-2005 review.
  • Systèmes auto-emulsionnables et émulsions sèches [Self emulsifying drug delivery systems]

2004年

  • Structural and thermal characterization of lipidic excipients and carriers by X-ray diffraction coupled to differential microcalorimetry
  • Structural and thermal characterization of mono and diacyl polyoxyethylene glycol by infrared spectroscopy and X-ray diffraction coupled to differential calorimetry

2003年

  • Enhanced bioavailability of simvastatin in a self-emulsifying drug delivery system (SMEDDS)
  • Development of immediate release pellets of poorly soluble compounds using Gelucire® 44/14
  • Comparative study of the lubricant performance of Compritol® 888 ATO either used by blending or hot melt coating
  • Comparative study of the lubricant performance of Compritol® HD5 ATO and Compritol® 888 ATO: effect of polyethylene glycol behenate on lubricant capacity